A new low-molecular-weight component promoting adrenergic development in cultured chick sympathetic neurons
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چکیده
منابع مشابه
A new low-molecular-weight component promoting adrenergic development in cultured chick sympathetic neurons.
A low-molecular-weight component present in medium conditioned by cultured chick liver cells (LCM) enhances the adrenergic properties of dissociated chick superior cervical ganglion (SCG) neurons in culture (Zurn and Mudry, 1986). This substance cannot replace NGF as a survival, growth, or differentiation factor. However, in the presence of NGF, it stimulates neuronal metabolism and catecholami...
متن کاملGrowth cones of cultured sympathetic neurons contain adrenergic vesicles
The growth cones of dissociated rat sympathetic neurons developing in culture were fixed with potassium permanganate to visualize vesicular stores of norepinephrine through the formation of granular precipitates. It was found that growth cones contain numerous small granular vesicles (SGV) 40-60 nm in diameter. The majority of the SGV was present in the varicosity of the growth cone but SGV als...
متن کاملAxonal Agranular Reticulum and Synaptic Vesicles in Cultured Embryonic Chick Sympathetic Neurons
Cultured chick embryonic sympathetic neurons contain an extensive axonal network of sacs and tubules of agranular reticulum. The reticulum is also seen branching into networks in axon terminals and varicosities. The axonal reticulum and perikaryal endoplasmic reticulum resemble one another in their content of cytochemically demonstrable enzyme activities (G6Pase and IDPase) and in their charact...
متن کاملGlycine receptors in cultured chick sympathetic neurons are excitatory and trigger neurotransmitter release.
1. Total RNA isolated from embryonic chick paravertebral sympathetic ganglia was used in a reverse transcription-polymerase chain reaction (RT-PCR) assay with a pair of degenerate oligonucleotide primers deduced from conserved regions of mammalian glycine receptor alpha-subunits. Three classes of cDNA were identified which encode portions of the chicken homologues of the mammalian glycine recep...
متن کاملInducing dendritic growth in cultured sympathetic neurons.
The shape of the dendritic arbor determines the total synaptic input a neuron can receive (1-3), and influences the types and distribution of these inputs (4-6). Altered patterns of dendritic growth and plasticity are associated with impaired neurobehavioral function in experimental models (7), and are thought to contribute to clinical symptoms observed in both neurodevelopmental disorders (8-1...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1987
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.07-11-03566.1987